MOLSID’s innovative technology platform, termed SmartID®, consists of unique enzyme-responsive biotracers that generate a fluorescent precipitate at the site of the enzyme’s activity.
This opens the possibility to design new IVD test kits with unprecedented performance when combined with a dedicated fluorescence reader.
MOLSID has a portfolio of more than twenty operational biotracers that can be used in a wide range of applications as staining agents to detect cancerous tissue or bacterial pathogens, for example, but also to monitor cell growth by tracking the activity of specifically selected enzymes.
In addition, MOLSID has developed biotracers that responds to all beta-lactamase activities. beta-lactamases are a family of enzymes expressed by resistant bacteria that inactivate beta-lactam antibiotics. This mechanism is responsible for the most critical cases of antimicrobial resistance in the world. This unprecedented portfolio of substrates has enabled us to develop kits for the rapid detection of antibiotic resistance.
Imaging Enzymes at Work: Metabolic Mapping by Enzyme Histochemistry
Published : juillet 4, 2022
“2-(2’-Phosphoryloxyphenyl)-4(3H)-quinazolinone, Derivatives as Fluorogenic Precipitating, Substrates of Phosphatases”
Published : juillet 4, 2022
“A robust, high-sensitivity stealth probe for peptidases”
Published : juillet 4, 2022
Metabolic Mapping by Enzyme Histochemistry in living animals, tissues and cells
Published : juillet 4, 2022
Ultrahigh‐Throughput FACS‐Based Screening for Directed Enzyme Evolution
Published : juin 28, 2022
Enzyme Cytochemical Techniques for Metabolic Mapping in Living Cells, with Special Reference to Proteolysis
Published : juin 28, 2022
Imaging Enzymes at Work: Metabolic Mapping by Enzyme Histochemistry
Published : juin 28, 2022
“Double gating” – a concept for enzyme-responsive imaging probes aiming at high tissue specificity
Published : juin 28, 2022
Tagging Live Cells that Express Specific Peptidase Activity with Solid‐State Fluorescence
Published : juin 28, 2022
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